Progynova is an oestrogen-only hormone replacement therapy (or HRT for short) which commonly prescribed throughout the UK to mitigate the uncomfortable symptoms of menopause. Developed and marketed by Bayer pharmaceutical company, Progynova is available both as a tablet and a transdermal patch, with both forms being available in two different strengths. As such, Progynova can be safely used even by women who are especially prone to experiencing side effects associated with this medication.

What’s on this page?

Classified as a continuous HRT in the tablet form, Progynova transdermal patch can be used both continuously and cyclically in agreement with the doctor. The patch form is usually marketed under the name Progynova TS.

When should I seek HRT?

Menopause is, of course, a completely natural process that every woman will experience after reaching a certain age. As such, menopause cannot be cured nor prevented – and there is no reason for this. The cluster of symptoms associated to menopause is actually a consequence of natural changes in the female body as it approaches the final ovulation and afterwards. These changes are, for most of the time, closely related to changes of levels of different hormones, most notably oestrogen. In fact, the vast majority of symptoms associated with menopause are directly tied to the decrease in overall presence of oestrogen within the body.

These symptoms are thought of as rather mild by a majority of women and in those cases, no additional therapy or remedy will be needed. However, in those cases where they become especially prominent and severe to the point of interfering with everyday life and activities, prescription medication in form of hormone replacement therapy such as Progynova might be advised.

How can Progynova make menopause less uncomfortable?

As mentioned, the decreasing levels of oestrogen are at the root of the majority of issues commonly associated with menopause, so it comes as no surprise that HRTs such as Progynova aim to solve this problem by providing the body with synthetic, man-made bioequivalent of the said sex hormone. Progynova is no different – it is based on estradiol hemihydrate as an active ingredient, a pharmaceutical compound that mimics the effects of oestrogen on the body. Once introduced into the bloodstream, this compound will successfully supplement the decreasing levels of oestrogen and thus alleviate the symptoms associated with this deficit.

As an oestrogen-only solution, Progynova is recommended to women who have already undergone hysterectomy, a surgical procedure that involves the removal of the womb, similarly to other medications of the same type (such as Estradot). This is very important since uncontrolled rise in the levels of oestrogen has been proven to cause excessive thickening of uterine lining which can eventually develop into endometrial cancer. Because of this, oestrogen-only HRTs can be safely used either by women who have had their wombs removed or those which take additional supplements based on synthetic progesterone, a compound that is tasked with keeping the oestrogen levels in check.

Progynova as a second-line osteoporosis treatment

Studies have also shown that Progynova can achieve measurable results when prescribed to postmenopausal women who are at risk of developing osteoporosis. However, despite this, Progynova remains second-line osteoporosis treatment which is prescribed only to those women who are unable to take other, prime-line solutions for one reason or another.

How to use Progynova?

Before commencing treatment, be sure to carefully read through the official patient information leaflet that is issued within every pack of the medicine. There you will find crucial information on when and how exactly to commence the treatment and how to ensure optimal results while at the same time minimising the risk of experiencing side effects. In addition to this, your prescriber will certainly provide you with additional, maybe even personalised instructions, which should always be your first point of reference.

In the text bellow, we will provide you with some of the most central and most general guidelines for Progynova use. However, you should keep in mind that what follows is in no way intended to be used as a substitute for the official information contained in the patient information leaflet, nor for the doctor’s instructions. Instead, what follows is an illustration that should help you get a better understanding of what Progynova treatment might involve and what should you keep in mind when using this medication.

How to use Progynova tablets?

  • Take one tablet each day without chewing or breaking them
  • Start with the correct day of the week on the top row of the pack (indicated by blue colour)
  • Follow the arrows printed on the pack until you used up all the tablets
  • Ideally, try to take each tablet at the same time each day
  • If you forget to take a dose, you can take it as long as no more than 12 hours have passed since the scheduled time
  • If more than 12 hours has passed, just skip the dose and continue with the treatment as usual
  • If this is the case, be sure to continue from the tablet on the appropriate place in the strip (leave the skipped dose in the strip)
  • Never double the dose to compensate for the missed one

How is Progynova TS patch used?

  • Remove the protective sheet from the patch
  • Apply the patch to clean, dry and uninjured area of skin
  • Ideally, apply the patch to buttocks or lower body
  • Change patches every seven days while using different area of skin each time
  • Never place patches on the breasts, waist or genitals
  • If the patch falls of prematurely, simply replace it with the new one, without changing the course of the treatment
  • If you forget to replace a patch, simply replace it when you do remember and continue with the treatment as usual
  • Never wear more than one patch at the time

What are Progynova side effects?

As is the case with most medications, Progynova comes with some possible side effects. Those can be classified in two categories, those which are a serious reason for concern and those which are uncomfortable, but benign. We will quickly mention some of them.

You should immediately halt your treatment and contact your doctor or the local emergency service if you notice any of the following:

  • Jaundice
  • Sharp increase in blood pressure
  • Symptoms of blood clot
  • Chest pain
  • Painful redness and swelling in the legs
  • Sudden onset of migraines (without prior history)

Other documented side effects include:

  • Breast tenderness or pain
  • Unexplained vaginal bleedings
  • Depression
  • Nausea
  • Headaches
  • Flatulence
  • Fluid retention
  • Weight gain
  • Irregular periods
  • Skin rashes
  • Anxiety
  • Mood swings
  • Sleep disturbance
  • Changes in libido
  • Mood changes
  • Pins and needles
  • Trembling
  • Palpitations
  • Hypertension
  • Hair loss or hair growth
  • Breast discharge
  • Increased size of the fibroids in the womb