Developed by Allen and Hanburys, Flixotide is a preventer asthma treatment designed for the alleviation of inflammation of the affected parts respiratory system in asthmatics. By doing this, Flixotide makes a flare-up of symptoms (also known as an asthma attack) significantly less likely. The active ingredient of this medicine, fluticasone, is administered into the organism via a specialized device which comes in two forms:

  • Evohaler – a device similar to a conventional inhaler
  • Accuhaler – a device without propellant, similar to dry powder inhaler (DPI)

The common dose of Flixotide is usually two puffs, taken twice per day. However, the severity of the condition can lead to further increase in dosage, if the doctor agrees to it.

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Flixotide in asthma treatment

This very effective preventer is a branded product, available in two different forms, suitable for different patients. Its introduction to the UK markets means yet another option for more than 5 million people affected by this condition in the United Kingdom alone.

While there is no consensus as of now on what exactly causes asthma, some potential factors have been identified, including:

  • Increased sensitivity to airborne irritants
  • Over-activity of the immune system
  • Hereditary and genetic factors

Most of the asthma episodes are triggered by certain common elements (called triggers), such as the presence of allergens in the air, cold air, smoke, dust or chemical particles and fumes. Even intense physical activity can cause an asthma attack in some (this is usually called exercise-induced asthma).

Flixotide belongs to a class of asthma treatments called preventers. As opposed to relievers which are used when needed in order to alleviate the acute symptoms of an asthma attack, preventers are used on a regular basis in order to reduce the chances of experiencing an asthma attack at the first place. Fluticasone, a type of corticosteroid utilized by Flixotide does this by inhibiting the release of the chemicals immune system naturally generates in response to irritants.

How to use Flixotide?

Similarly to other inhalers such as Ventolin, Flixotide is relatively easy to use. The detailed instruction will be provided by your doctor and also on the official leaflet. Here, we will mention just some of the most general considerations that should help you increase the effectiveness of the treatment, while minimizing the chances for side effects at the same time.

  • Use the medicine in accordance with doctor’s advice
  • Disclose the details of the severity of your condition to the doctor so he can recommend you a proper dosage
  • Mild asthma is usually treated with 100 micrograms, twice a day
  • Moderate to severe asthmatics may need 250-500 micrograms twice a day
  • Your daily intake should never exceed two doses of 1000 micrograms
  • If you have been using Flixotide for prolonged periods of time, do not stop taking it suddenly or without consulting the doctor beforehand

How to use Flixotide evohaler?

  • Shake before use and remove the cover
  • Test the device by releasing a couple of test shoots safely into the air
  • Calm down your breathing and sit or stand in an upright position
  • Exhale fully
  • Place the end of the evohaler between lips
  • Breath in and press down on the canister at the same time
  • Hold your breath for a couple of seconds
  • Wait one minute before repeating the process for another puff

How to use flixotide accuhaler?

  • Open the casing by pushing back the thumb grip until you hear a click
  • Hold the accuhaler with the opening pointing towards you
  • Push back the lever until it clicks
  • Exhale fully
  • Put the accuhaler against your mouth and inhale
  • Hold your breath for at least 10 seconds
  • Close and reset the device by pulling the thumb grip towards you
  • Repeat the process for an additional dose

What are Flixotide side effects?

As is the case with all prescription medication, Flixotide also comes with certain potential side effects. Of course, while not everybody will experience these, it is still important to be aware of them, so you can notice them right away if they do manifest and seek medical attention, or ask your doctor for a change of treatment. If you experience symptoms of an allergic reaction or exacerbation of asthma symptoms right after use, contact your doctor immediately.

Oral thrush is usually singled out as the most common side effect that manifests in 1 in 10 patients taking this treatment. Somewhat less common and observed in less than 1 in 10 patients are the soreness in the tongue or throat and hoarseness. Oesophageal thrush is observed in 1 in a 1000 patients and finally, very rare side effects, documented in 1 in 10.000 patients include insomnia, anxiety, joint pain, indigestion and rise in sugar levels in the blood.

Flixotide precautions and contraindications

In addition to side effects that may manifest, there are some additional issues that one should keep in mind, most notably, the possible interactions with other medicines and conditions or factors that might be problematic if you consider this treatment. Here we will explore those questions in more detail.

Flixotide interactions

Flixotide is known to interact with several commonly used medicines including:

  • Protease inhibitors (ritonavir)
  • Antifungal medicines (ketoconazole)

Are there any conditions that I should mention to my doctor?

While Flixotide hasn’t been known to aggravate any pre-existing conditions, you should still inform your doctor about your medical history and current health issues (if any), just in case.

Can I drink alcohol when on this medicine?

There are no known interactions between this type of asthma treatment and alcohol, so the effectiveness of the treatment won’t be diminished, nor will the effects of intoxication be exacerbated.

Driving and machine use

Flixotide is not likely to impair your driving or machine operating skills, so you should encounter no problems there. However, if you do notice some side effects such as dizziness, it’s better to avoid driving until you sort that issue out with a doctor.

Flixotide, pregnancy and breastfeeding

Regarding this question, it is best to consult with a doctor regarding the details. In general, inhalators should have no effects on the baby, whether they’re used during pregnancy or while breastfeeding. However, certain higher dosages might increase the concentration of the medicine that is transmitted to the baby, so it’s better not to make decision on this issue without prior consultations with a medical professional.

How do I store this medicine?

Flixotide should be kept in a safe environment, ideally at a temperature below 30 degrees Celsius.

Can I buy Flixotide without prescription in the UK?

No, throughout Europe, Flixotide is a prescription-only medicine, so the only way to obtain it legally is with a prescription. It can be obtained either through direct face-to-face meeting with your doctor, or via an online clinic, through digital consultations with a certified medical professional.