Levitra is a very successful impotence medication based on the active ingredient vardenafil. It is sold under trade names Staxyn (India) and Vivanza (Italy) and used by men all over the world to bring their sex life back on track. Structurally and chemically similar to sildenafil, the active ingredient of Viagra, it relies on a similar mechanism of action in order to remove all physiological obstacles to gaining and maintaining a strong erection.

As such, Levitra is classified as a PDE-5 inhibitor. This means that it belongs to a unique class of pharmaceutical compounds, together with Viagra and Cialis, that is characterized by its unique mechanism of action – selective inhibition of phosphodiesterase type 5 enzymes (PDE-5 for short) and subsequent relaxation of smooth muscle tissue lining the blood vessels. In this way, Levitra supports the body’s natural mechanisms and processes instead of working against them, making it very safe and non-intrusive.

What’s on this page?

Can I buy Levitra online?

In the present day, you can buy almost anything online, and the same goes for Levitra. However, keep in mind that this is a prescription-only medicine, so the only way to legally buy Levitra online is through an online clinic. In this way, you will first go through consultations with a medical expert, either through live chat or a customized questionnaire. Once the doctor is assured that this treatment is safe and suitable for you, he will issue you a prescription and the medicine will be delivered to your address.

Can I buy Levitra without prescription?

Any vendors that might offer you to buy Levitra without prescription should better be avoided. It can be either illicitly obtained medicine or a counterfeit. In either case, there are significant risks with this kind of offers since you have no idea what exactly are you buying or how your organism will react to it.

Remember, the only way to legally and safely buy prescription medicine online is through an online clinic!

How does Levitra compare to Viagra?

As mentioned, Levitra is very similar to Viagra in terms of its chemical structure and the two also share the same mechanism of action. What’s more, Levitra is significantly more comparable to Viagra than Cialis, most notably in terms of structure, since the only difference between the two is the position of a nitrogen atom and the change of piperazine ring methyl group characteristic to sildenafil to an ethyl group. The relation between these compounds is also visible from their chemical formulas – C23H32N6O4S  1 for Levitra and C22H30N6O4S for Viagra.

Needless to say, the two have very similar onset times, available dosages and duration, but also come with a similar array of potential side effects and contraindications. These questions will be tackled in more detail below.

How does it work?

The mechanism of action of Levitra is the same as with all other PDE-5 inhibitors. In short, it inhibits the action of PDE-5 enzymes within the body. This is at the core of its effectiveness since PDE-5 enzymes are tasked with driving the blood away from the penis after ejaculation in order to prevent injury or the onset of conditions such as priapism. But, in men diagnosed with impotence, the levels of PDE-5 are usually significantly elevated. As a result, erection either lasts too short or doesn’t occur at all.

This is because PDE-5 acts by degrading cyclic guanosine monophosphate, or cGMP for short, a molecule that plays a crucial role in the relaxing the smooth muscle tissue around the arteries within the penis, causing stronger blood inflow within the spongy tissue of the penis and subsequently, an erection. Without cGMP molecules, this process is impossible.

Once Levitra is introduced to the organism, it acts as a competitive binding agent of PDE-5 due to structural similarities with cGMP. The result is the return of cGMP concentration to levels observed in healthy males. Once this is achieved, the task of Levitra is completed.

How fast does Levitra act and what’s the duration of effects

Despite all the similarities, Levitra is somewhat faster-acting that Viagra, with its effects being noticeable in as little as 15 minutes after taking the dose. Once medicine acts, it will continue doing so for the next five hours. However, it’s important to note that you can only take one Levitra tablet per day, so if you’re looking for an ED treatment that will last for longer periods of time, your doctor will probably recommend you Cialis as an alternative.

How is it used?

Levitra is available in two forms. The most common one is “classic” Levitra tablet, available in 5mg, 10mg and 20mg. The tablet should be taken 15 minutes to half an hour before sexual activity, with or without water or food. However, it’s important to mention that if you take too much food (especially if it contains a significant amount of grease or oil), the effects might take longer to manifest.

For total discretion, there is also Levitra Orodispersible, also in the form of a tablet, but available only in 10mg dosage. This type of Levitra will dissolve within the mouth, leaving a cool, minty aftertaste. It’s especially suitable for those who find that taking a tablet ruins the mood or those who are not fans of tablets in general.

What are the side effects and can I use it?

The doctor will be the one who will make the final decision on whether you’re suitable for Levitra treatment. However, there are some general contraindications to be aware of. To cover just a few most common ones, you shouldn’t use Levitra if:

  • You had a heart attack or a stroke
  • You had a life-threatening irregular heartbeat within last 6 months
  • You have angina pectoris
  • You have blood pressure issues

On the other hand, we can also mention some of the most common side effects that manifest in a percentage of patients who have been prescribed Levitra treatment. These include:

  • Headache
  • Indigestion
  • Flushing of the face
  • Dizziness
  • Stuffy nose


  1. Open Chemistry Database – Vardenafil