Kliofem is a hormone replacement therapy (or HRT for short) developed and marketed by Novo Nordisk pharmaceutical company. As a combination treatment, Kliofem contains two active ingredients, synthetic versions of naturally produced hormones oestrogen and progesterone. Highly adept at tackling the uncomfortable symptoms of menopause, due to its combination nature, Kliofem is prescribed to women who have not undergone a hysterectomy.

What’s on this page?

With just one pill per day, this medication can successfully keep the decreasing levels of oestrogen in check, at the same time preventing them from rising too much and causing issues associated with that process. As a continuous treatment, Kliofem is to be used every day in the same time, with the calendar strip containing the pills helping the user stay on course with the treatment.

When should I seek medical help?

Menopause is, of course, a completely natural process and as such, it will affect every woman at certain age. However, while the majority of women will notice just mild symptoms, there are some will notice more extreme complications which can begin to interfere with the everyday activities and general wellbeing. If this occurs, the doctor is likely to recommend prescription medication, or more precisely, hormone replacement therapy which will counteract the decrease in oestrogen levels. Women who haven’t had their wombs removed will be issued combination HRTs that will bring the hormone levels back to balance.

In this case, oestrogen-only HRTs can’t be used by themselves since additional progesterone treatment will be necessary in order to prevent excessive thickening of the uterine wall and subsequent risk of cancer. Women who have undergone hysterectomy can, on the other hand, use oestrogen-only treatments without issues.

How does Kliofem alleviate menopause symptoms?

As was implied, there are several different types of HRTs, with Kliofem and Kliovance belonging to a category called continuous combined HRTs. It helps mitigate the uncomfortable symptoms of menopause by supplementing the decreased levels of oestrogen by the synthetic version of the compound, namely estradiol. In addition to this, Kliofem also contains synthetic progesterone norethisterone that is tasked with keeping oestrogen levels in check, preventing them from raising so much to begin posing a threat to health and wellbeing of the user of the medicine. Due to presence of not one but two active ingredients, Kliofem is classified as a combined HRT.

Can I buy Kliofem online in the UK?

Yes, it is possible to buy Kliofem online, however, if it is your first time using this medication, you will be required to obtain it via the traditional route – by visiting the doctor in person and consulting about your suitability for using this medication. On the other hand, if you are looking to simply renew your prescription, you can do this without leaving the comfort of your home.

Most online clinics operating within the United Kingdom will provide you with a way to consult with a doctor using the functionality of their website. You are likely to be presented with a customised medical questionnaire that you will have to fill in so that the doctor can use that information to determine your suitability for using this medication. If everything is in order, the prescription will be issued and used that very same moment to have the treatment delivered from the partner pharmacy to the address you provided.

How is Kliofem used?

When using this medication, it is of uttermost importance to precisely follow the instructions provided by your prescriber. By doing so, you will ensure that the results of the treatment will be best they can and at the same time, you will significantly reduce the risk of experiencing side effects. In this part of the article, we will provide you with some of the most general guidelines for using Kliofem. However, you should keep in mind that this is not a comprehensive guide and cannot be used as a substitute to the information provided in the official patient information leaflet.

  • Always take as instructed
  • The usual dose is one pill at the same time each day
  • Tablets are preloaded in a disk called calendar pack, designed to help you keep track of your treatment
  • Take pills whole, with water if needed, without chewing of breaking them
  • Never exceed the prescribed dose
  • If you forget a pill, try to take it within 12 hours – if this is not possible and your next dose is due, just skip the missed dose
  • Advice on when to start treatment for optimal results can be found in the official patient information leaflet

What are Kliofem side effects?

As is the case with all prescription medications, Kliofem also comes with certain potential side effects. And while not everybody using this medication will necessarily experience them, it is still important to be able to differentiate between those side effects which are uncomfortable but harmless and those which might be a cause for concern and which might require you to seek immediate medical attention.

You should immediately contact your doctor if you notice any of the following:

  • Signs of breast cervical or ovarian cancer
  • Allergic reaction
  • Heart attack
  • Stroke
  • Angina
  • Blood clot
  • Liver failure

Other side effects include:

Frequency of occurrence Side effects
Very common (1 in 10 users or more) Breast pain and tenderness, unexplained vaginal bleeding
Common (1 in 10 users or less) Headache, vaginal inflammation, fluid retention, weight gain, migraine, fungal infections, depression, feeling sick, stomach pain, swelling of the breasts, back pain, cramps, fibroids in the uterus, swelling in the arms and legs
Uncommon (1 in 100 users) Flatulence, acne, hair loss, itching or hives, inflammation of a vein, anxiety
Rare (1 in 1000 users) Blood clots in the legs or lungs

Please keep in mind that this is not a full list of all documented side effects. For a more comprehensive overview, please refer to the official patient information leaflet that you can find within your pack of Kliofem.