Uric acidity is often referred to as podagra. It is an inflammation in joints due to the fact that crystals of uric acid are common in the joints. Because of the inflammation, the joint becomes painful, hot, red and swollen.

Zyloric is indicated to reduce or prevent the formation of urate / uric acid deposition under conditions where the body produces too much of a substance called uric acid. These may include gout or any type of kidney stones or cancer treatments.

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Causes of Podagra

High levels of uric acid in the blood and imbalance in uric acid levels trigger gout. The attacks are seen in major tissue damage, surgery, hunger, severe diarrhoea with fluid loss, thirst, diuretic drugs, by ingestion of all types of alcohol or without prior notice. Sometimes abundant intake of purine-containing foods, such as food, peas, beans, sardines, yeast and beer, can cause seizures.

Uric acid is one of the body’s wastes that are secreted through the kidneys. As the amount of uric acid in the body increases, uric acid crystals may be excreted in the joints and acute inflammation of the joints occurs. However, elevated uric acid content in the blood does not necessarily lead to uric acid levels.

There are many reasons why the amount of uric acid in the body increases:

  • Some have inherited an increased risk
  • Some people eat large quantities of foods that, among other things, break down into uric acid, such as meat, feed, mackerel and anchovy
  • Certain diseases with high cell turnover, eg psoriasis, increase uric acid levels
  • In case of renal impairment, less uric acid is secreted. The same is true of drinking alcohol, which is a frequent cause of acute urinary acne
  • High intake of fruit sugar (fructose). In particular, there is a problem with greater intake of sweet soda drinks, which are industrially added to fructose-containing sugars. Intake of sweet fruit in normal amounts hardly poses any problem, and due to the fruit’s otherwise beneficial effects on health do not discourage a regular consumption of sweet fruit
  • Artificially sweetened soda drinks do not lead to an increase in the concentration of uric acid in the blood

There are also other factors that ensure high blood urea levels in the blood:

  • Too high alcohol consumption, especially beer
  • High intake of red meat
  • Overweight
  • The combination of heart disease, high blood pressure, diabetes and high cholesterol
  • Use of certain medicines, such as diuretic medications against high blood pressure and common acetylsalicylic acid

Symptoms of Gout

Joint pain usually occurs abruptly, usually over a few hours. Osteoarthritis usually occurs as an attack. But there are other symptoms than that. Generally, urinary systolic affects the root of the big toe, but also other joints in the foot, ankle, knee, wrist, fingers, or elbow can be painful. It usually appears that you experience acute swelling, redness and pain in one single joint. The pain is violent, but they diminish within a week’s time. The uric acid can divert itself into the skin, where it is seen as small, gold-white nodules. If uric acid deposits in the kidneys, you may have kidney stones.

Clear crystals can also be formed under the skin of your hands, knees, wrists, elbows or ears. They look like white lumps, and the doctors call these lumps for tophi. The doctor will probably be able to diagnose uric acid by investigating. Probably you will also need a blood test to check how much uric acid you have in the blood.

During the attack, one feels sick, often with fever, sweating and nausea. The pain can eventually increase, especially about the nights, and the joints with the surroundings become so hot and swollen that it all can recall an infection. Upon examination of arthritis, plenty of typical pointed uric acid crystals are detected together with increased white blood cell count.

Zyloric as a treatment for Gout

Zyloric is indicated to reduce or prevent the formation of urate / uric acid deposition under conditions where the body produces too much of a substance called uric acid. These may include gout or any type of kidney stones or certain other types of kidney, or when you are being treated for cancer or other conditions.

Zyloric tablets contain the active ingredient allopurinol, a type of medicine that inhibits the conversion of purine (a substance found in high protein food), including uric acid. The excess of uric acid in the blood can cause a variety of health problems, such as gout and kidney stones. Zyloric lowers the level of uric acid in the body and thus helps to prevent or reduce the symptoms associated with these conditions. Treatment should be started at low doses and then gradually increase. It is not recommended for patients with known allergy history.

Zyloric side effects

Frequency of occurrence Side effects
Common (1 of 10 users) skin rash, increased level of thyroid stimulating hormone in the blood.
Uncommon (1 of 100 users) an increased level of thyroid stimulating hormone in the blood.
Rare (1 of 1000 users) Blood in the urine, high levels of cholesterol in the blood, high blood pressure
Very Rare (1 of 10.000 users) male infertility or erectile dysfunction, a change in normal bowel habits, hair loss or discoloration

Zyloric contraindications

All substances work differently from person to person. You should check all possible interactions with your doctor before starting any medicine. Do not use Zyloric if you are pregnant or trying to conceive. You should only use this medicine with your doctor’s approval if you are breastfeeding. Zyloric does not affect the ability to react or drive safely, but if you feel relaxed and tired, consult your doctor before continuing treatment. While alcohol can affect the effect of Zyloric. It is therefore important to reduce alcohol intake or stop completely while taking this medicine.

You should not use this medicine if:

  • if you suffer from severe liver or kidney failure.
  • If you have an acute attack of uric acid, treatment with Zyloric should not be started before the acute attack is over. At high concentrations of uric acid you should drink plenty.
  • if you have heart problems or high blood pressure and you are taking diuretics (diuretics) and / or so-called ACE inhibitors.
  • If you have problems with thyroid gland.

Can I buy Zyloric online in the UK?

You can buy this medicine from an online clinic. But first you need to fill out a medical form, then get medical advice if you are fit for the treatment. Your doctor will then review your form to ensure that the product is suitable for you. Once approved, the order generates an electronic prescription received by their co-operating pharmacy. The drug will then be dispensed and packed for delivery to the doorstep.

Note that this medicine is not sold without a prescription in the UK, so it is important to be aware of websites selling this medicine without the need for a prescription. These drugs may contain illegal substances that may be dangerous to you and your health.

If you are taking other medicines and are not sure if this medicine will work negatively with other means you use, always provide such information through the consultation method you choose.